New study at UW Health for those suffering with lingering pain
A new study at the University of Wisconsin Hospital and Clinics (UW Health) is currently accepting patients who suffer with lingering pain following an injury in their hands, arms, legs, or feet. Chronic, intense pain following an injury or trauma, typically to the arms, hands, feet, or legs, is called Complex Regional Pain Syndrome (CRPS). […]
A new study at the University of Wisconsin Hospital and Clinics (UW Health) is currently accepting patients who suffer with lingering pain following an injury in their hands, arms, legs, or feet.
Chronic, intense pain following an injury or trauma, typically to the arms, hands, feet, or legs, is called Complex Regional Pain Syndrome (CRPS). CRPS typically develops following a fracture (in the ankle or wrist) or after surgery.
According to the Mayo Clinic’s website , CRPS typically develops after an injury, surgery, stroke, or heart attack, but the pain is out of proportion to the severity of the initial injury.
The cause of complex regional pain syndrome isn’t clearly understood and treatment for complex regional pain syndrome is most effective when started early. In such cases, improvement and even remission are possible.
Signs and symptoms of complex regional pain syndrome include:
- Continuous burning or throbbing pain, usually in your arm, leg, hand or foot
- Sensitivity to touch or cold
- Swelling of the painful area
- Changes in skin temperature — at times your skin may be sweaty; at other times, it may be cold
- Changes in skin color, which can range from white and mottled to red or blue
- Changes in skin texture, which may become tender, thin or shiny in the affected area
- Changes in hair and nail growth
- Joint stiffness, swelling and damage
- Muscle spasms, weakness and loss (atrophy)
- Decreased ability to move the affected body part
However, symptoms can change over time.
CRPS is considered one of the most painful types of chronic pain, and it can take a major toll on one’s quality of life.
The study is being conducted by trained, qualified, licensed physicians and medical specialists and is expected to last about six to seven months.
University of Wisconsin Hospital and Clinics is a 592-bed academic medical center with 85 outpatient clinics in Madison, Wisconsin.
For the study, doctors at select centers in the U.S., U.K., Canada, and Australia are currently accepting participants for the CREATE-1 Clinical Study. The study is for an investigational oral medication that may help improve CRPS symptoms.
Participants will receive all study-related care at no cost, which includes study medications and medical visits. Participants may also be compensated for their time and travel during the study.
To learn more, or to see if you qualify to participate, visit www.crpstrial.com/.









